Genipin 1-beta-gentiobioside
Genipin 1-Gentiobioside
CAS: 29307-60-6
Molecular Formula: C23H34O15
Genipin 1-beta-gentiobioside - Names and Identifiers
Genipin 1-beta-gentiobioside - Physico-chemical Properties
| Molecular Formula | C23H34O15 |
| Molar Mass | 550.51 |
| Density | 1.63±0.1 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 193-195°C |
| Boling Point | 835.3±65.0 °C(Predicted) |
| Flash Point | 281°C |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Vapor Presure | 2.16E-32mmHg at 25°C |
| Appearance | White crystalline powder |
| pKa | 12.78±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.647 |
| Physical and Chemical Properties | It is soluble in methanol, ethanol, DMSO and other organic solvents, and comes from the dried mature fruit of jasminoides Ellis, a Rubiaceae plant gardenia Gardenia Rubiaceae. |
| In vivo study | Genipin 1-β-D-gentiobioside (Genipin gentiobioside) has moderate terminal elimination half-life (t 1/2 =1.65±0.87 h and 2.43±2.30 h for nomal rats (11.4 mg/kg) and cholestatic liver injury (CLI) rats (11.4 mg/kg), respectively). |
Genipin 1-beta-gentiobioside - Reference
| Reference Show more | 1. Liu, Hong, Lei, Lu, Jing, Bai, Yuqin, et al. Simultaneous determination of seven index components in Mongolian medicine Sanzi powder by one-Test multi-evaluation method [J]. Chinese Journal of Experimental prescriptions, 2017, 023(018):58-63. 2. Miao Qi, Luo Yang, Fang Wenjuan, et al. Simultaneous determination of six components in Gardenia jasminoides Ellis by one-Test multi-evaluation method [J]. Jiangsu Agricultural Sciences 2015 43(001):292-295. 3. Luo Guang-ming, Yuan Yuan, Miao Qi, et al. Based on the influence of topographic factors on the contents of six components in Gardenia jasminoides Ellis and the study on ecological suitability [C]// Chinese traditional medicine resources conference and csnr annual meeting of Chinese medicine and natural medicine resources Research Committee. 2016. 4. Peng Ping, Zhang Bei, Du Jing, et al. Quality Characterization of characteristic chromatograms of Angong Niuhuang pills based on natural musk-calculus Bovis and four plant herbs [J]. Chinese herbal medicine, 2019(14). 5. Gong Yuhong, Luo Guangming, Zhang Fengbo, Yuan Yuan, Li Bo, Xiao richuan, Xie Jing, Zhang Bowen. Evaluation of quality of Gardenia jasminoides Ellis based on gray correlation degree [J]. Chinese Journal of Experimental prescriptions, 2017,23(13):74-79. 6. Miao Qi, Hu Yanzhen, Luo Guang Ming, etc. Establishment of multi-wavelength HPLC method for index components of Gardenia jasminoides Ellis in national production regionalization [J]. Jiangsu Agricultural Sciences, 2015, 43(002):300-302. 7. Study on multi-wavelength HPLC fingerprint and chemical pattern recognition of Gardenia jasminoides Ellis [J]. Chinese herbal medicine, 2014, 45(21): 3169-3164. 8. Yuan Yuan, Luo Guang-ming, Wei Chunhua, etc. Study on correlation between color and six components of gardenia fruit peel [J]. Shi Zhen, National Medicine, 2016, 027(006):1480-1483. 9. Shao Jian, Luo Guang-ming, Zhu Jixiao, etc. Comparative study on seven components of gardenia before and after processing [J]. Chinese Herbal Medicine, 2015, 46(11). 10. Tian Ruihua, Peng Ping, Liu Xi, et al. Study on the correlation between the quality characterization and the origin of gardenia [J]. World Science and Technology: modernization of traditional Chinese medicine, 2019(5):882-891. 11. Li-hang, Cha-Yi-Fan, He Fengyan, Liu Jing, Li Jing, Dai Zhong, Yu Jiandong, Ma Shuangcheng. Establishment of control preparation of Niuhuang Qingwei pill [J]. Journal of Pharmaceutical Analysis, 2019,39(10):1738-1750. 12. Qian, Shi Yanhong, Chen Shaocheng, et al. Determination of four components in Gardenia by UPLC [J]. Chinese traditional medicines, 2016, 38(3):708-711. 13. Cao Honghong, Yan Weihua, Guo Shuang, etc. Quality Evaluation of gardenia from different habitats based on multi-component determination and fingerprint [J]. Chinese Journal of Traditional Chinese Medicine, 2019, v.44(18):196-203. 14. Honghong Cao, Yan Weihua, Guo Shuang, et al. Study on processing technology of gardenia and changes of chemical composition of ginger before and after processing [J]. Chinese Journal of Traditional Chinese Medicine, 2019, 26 (24). 15. Miao Zhi-Shuo, Zhong Yi-ling, Li Hai-Li, Wu Qian, Yi Ding, Tang Wei-Zhuo. LC-MS analysis and HPLC-DAD determination of seven components in the branches of Gardenia jasminoides [J]. Chinese patent medicine, 2021,43(01):117-123. 16. Wang, Lu, et al. "Characterization of interaction property of multi-components in Gardenia jasminides with aldose reduction by microdialysis combined with liquid chromatography coupled to mass spectrum." Rapid Communications in Mass Spectroscopy 30 (2 17. Wang, Lu, et al. "Characterization of interaction property of multi‐components in Gardenia jasminoides with aldose reductase by microdialysis combined with liquid chromatography coupled to mass spectrometry." Rapid Communications in Mass Spectrometry 30 (2 18. [IF=4.759] Lu Wang et al."A strategy for identification and structural characterization of compounds from Gardenia jasminoides by integrating macroporous resin column chromatography and liquid chromatography-tandem mass spectrometry combined with ion-mobility spectr 19. [IF=2.419] Lu Wang et al."Characterization of interaction property of multi-components in Gardenia jasminoides with aldose reductase by microdialysis combined with liquid chromatography coupled to mass spectrometry."Rapid Communications In Mass Spectrometry. 2016 Au 20. [IF=1.902] Zhi Rao et al."Multicomponent determination of traditional Chinese medicine preparation yin-zhi-huang injection by LC-MS/MS for screening of its potential bioactive candidates using HepaRG cells."Biomed Chromatogr. 2018 Feb;32(2):e4057 21. [IF=5.81] Bai Yongtao et al."Integrated Network Pharmacology Analysis and Experimental Validation to Investigate the Mechanism of Zhi-Zi-Hou-Po Decoction in Depression."Front Pharmacol. 2021 Oct;0:2575 22. [IF=5.81] Dong Rong et al."An Integrated Strategy for Rapid Discovery and Identification of Quality Markers in Gardenia Fructus Using an Omics Discrimination-Grey Correlation-Biological Verification Method."Front Pharmacol. 2021 Jun;0:1596 23. [IF=4.411] Chunnan Li et al."Screening of the Hepatotoxic Components in Fructus Gardeniae and Their Effects on Rat Liver BRL-3A Cells."Molecules. 2019 Jan;24(21):3920 24. [IF=3.935] Biru Shi et al."Investigation on the stability in plant metabolomics with a special focus on freeze-thaw cycles: LC-MS and NMR analysis to Cassiae Semen (Cassia obtusifolia L.) seeds as a case study."J Pharmaceut Biomed. 2021 Sep;204:114243 25. [IF=2.447] Jianrong Chen et al."Anti‑inflammatory activities of Gardenia jasminoides extracts in retinal pigment epithelial cells and zebrafish embryos."Exp Ther Med. 2021 Jul;22(1):1-9 |
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Product Name: Genipin-1-b-D-gentiobioside Visit Supplier Webpage Request for quotationCAS: 29307-60-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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